Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells

To rescue collapsed replication forks cells utilize homologous recombination (HR)-mediated mechanisms to avoid the induction of gross chromosomal abnormalities that would be generated by non-homologous end joining (NHEJ). Using DNA interstrand crosslinks as a replication barrier, we investigated how...

Descripción completa

Detalles Bibliográficos
Autores principales: Renaud, Emilie, Barascu, Aurelia, Rosselli, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737135/
https://www.ncbi.nlm.nih.gov/pubmed/26446986
http://dx.doi.org/10.1093/nar/gkv1019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737135/
https://www.ncbi.nlm.nih.gov/pubmed/26446986
http://dx.doi.org/10.1093/nar/gkv1019

Ejemplares similares