Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks

The DNA damage checkpoint pathway is activated in response to DNA lesions and replication stress to preserve genome integrity. However, hyper-activation of this surveillance system is detrimental to the cell, because it might prevent cell cycle re-start after repair, which may also lead to senescenc...

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Detalles Bibliográficos
Autores principales: Dibitetto, Diego, Ferrari, Matteo, Rawal, Chetan C., Balint, Attila, Kim, TaeHyung, Zhang, Zhaolei, Smolka, Marcus B., Brown, Grant W., Marini, Federica, Pellicioli, Achille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737138/
https://www.ncbi.nlm.nih.gov/pubmed/26490958
http://dx.doi.org/10.1093/nar/gkv1080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737138/
https://www.ncbi.nlm.nih.gov/pubmed/26490958
http://dx.doi.org/10.1093/nar/gkv1080

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