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A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis

Differentiating erythroblasts execute a dynamic alternative splicing program shown here to include extensive and diverse intron retention (IR) events. Cluster analysis revealed hundreds of developmentally-dynamic introns that exhibit increased IR in mature erythroblasts, and are enriched in function...

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Detalles Bibliográficos
Autores principales: Pimentel, Harold, Parra, Marilyn, Gee, Sherry L., Mohandas, Narla, Pachter, Lior, Conboy, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737145/
https://www.ncbi.nlm.nih.gov/pubmed/26531823
http://dx.doi.org/10.1093/nar/gkv1168