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Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells. Some have important functions and their dysregulation can contribute to a variety of disease states. However, most lncRNAs have not been functionally characterized. Complicating their study, lncRNAs have widely vary...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737147/ https://www.ncbi.nlm.nih.gov/pubmed/26578588 http://dx.doi.org/10.1093/nar/gkv1206 |