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Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells. Some have important functions and their dysregulation can contribute to a variety of disease states. However, most lncRNAs have not been functionally characterized. Complicating their study, lncRNAs have widely vary...

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Detalles Bibliográficos
Autores principales:	Lennox, Kim A., Behlke, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737147/ https://www.ncbi.nlm.nih.gov/pubmed/26578588 http://dx.doi.org/10.1093/nar/gkv1206

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