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A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1

The YTH domain-containing protein Mmi1, together with other factors, constitutes the machinery used to selectively remove meiosis-specific mRNA during the vegetative growth of fission yeast. Mmi1 directs meiotic mRNAs to the nuclear exosome for degradation by recognizing their DSR (determinant of se...

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Detalles Bibliográficos
Autores principales: Wang, Chongyuan, Zhu, Yuwei, Bao, Hongyu, Jiang, Yiyang, Xu, Chao, Wu, Jihui, Shi, Yunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737157/
https://www.ncbi.nlm.nih.gov/pubmed/26673708
http://dx.doi.org/10.1093/nar/gkv1382