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Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF‐1r Onto the Primary Cilium Associated With Cilia Elongation
Primary cilia are single non‐motile organelles that provide a highly regulated compartment into which specific proteins are trafficked as a critical part of various signaling pathways. The absence of primary cilia has been shown to prevent differentiation of human mesenchymal stem cells (hMSCs). Cha...
Autores principales: | Dalbay, Melis T., Thorpe, Stephen D., Connelly, John T., Chapple, J. Paul, Knight, Martin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737234/ https://www.ncbi.nlm.nih.gov/pubmed/25693948 http://dx.doi.org/10.1002/stem.1975 |
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