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Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders

BACKGROUND: Observational studies show a strong association between delayed intestinal transit and the production of methane. Experimental data suggest a direct inhibitory activity of methane on the colonic and ileal smooth muscle and a possible role for methane as a gasotransmitter. Archaea are the...

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Detalles Bibliográficos
Autores principales: Gottlieb, K., Wacher, V., Sliman, J., Pimentel, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737270/
https://www.ncbi.nlm.nih.gov/pubmed/26559904
http://dx.doi.org/10.1111/apt.13469