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Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders
BACKGROUND: Observational studies show a strong association between delayed intestinal transit and the production of methane. Experimental data suggest a direct inhibitory activity of methane on the colonic and ileal smooth muscle and a possible role for methane as a gasotransmitter. Archaea are the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737270/ https://www.ncbi.nlm.nih.gov/pubmed/26559904 http://dx.doi.org/10.1111/apt.13469 |