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Extrinsic factors can mediate resistance to BRAF inhibition in central nervous system melanoma metastases
Here, we retrospectively review imaging of 68 consecutive unselected patients with BRAF V600‐mutant metastatic melanoma for organ‐specific response and progression on vemurafenib. Complete or partial responses were less often seen in the central nervous system (CNS) (36%) and bone (16%) compared to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737278/ https://www.ncbi.nlm.nih.gov/pubmed/26414886 http://dx.doi.org/10.1111/pcmr.12424 |