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Safety of PEGylated recombinant human full‐length coagulation factor VIII (BAX 855) in the overall context of PEG and PEG conjugates

INTRODUCTION: BAX 855 is a PEGylated human full‐length recombinant factor VIII (rFVIII) based on licensed rFVIII (ADVATE). The applied PEGylation technology has been optimized to retain functionality of the FVIII molecule, improve its pharmacokinetic properties and allow less frequent injections whi...

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Detalles Bibliográficos
Autores principales: Stidl, R., Fuchs, S., Bossard, M., Siekmann, J., Turecek, P. L., Putz, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737295/
https://www.ncbi.nlm.nih.gov/pubmed/26219204
http://dx.doi.org/10.1111/hae.12762