Melanopsin retinal ganglion cell loss in Alzheimer disease

OBJECTIVE: Melanopsin retinal ganglion cells (mRGCs) are photoreceptors driving circadian photoentrainment, and circadian dysfunction characterizes Alzheimer disease (AD). We investigated mRGCs in AD, hypothesizing that they contribute to circadian dysfunction. METHODS: We assessed retinal nerve fib...

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Detalles Bibliográficos
Autores principales: La Morgia, Chiara, Ross‐Cisneros, Fred N., Koronyo, Yosef, Hannibal, Jens, Gallassi, Roberto, Cantalupo, Gaetano, Sambati, Luisa, Pan, Billy X., Tozer, Kevin R., Barboni, Piero, Provini, Federica, Avanzini, Pietro, Carbonelli, Michele, Pelosi, Annalisa, Chui, Helena, Liguori, Rocco, Baruzzi, Agostino, Koronyo‐Hamaoui, Maya, Sadun, Alfredo A., Carelli, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737313/
https://www.ncbi.nlm.nih.gov/pubmed/26505992
http://dx.doi.org/10.1002/ana.24548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737313/
https://www.ncbi.nlm.nih.gov/pubmed/26505992
http://dx.doi.org/10.1002/ana.24548

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