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Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase–Phosphatase Combination Catalyst

Sugar phosphates play an important role in metabolism and signaling, but also as constituents of macromolecular structures. Selective phosphorylation of sugars is chemically difficult, particularly at the anomeric center. We report phosphatase‐catalyzed diastereoselective “anomeric” phosphorylation...

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Detalles Bibliográficos
Autores principales: Wildberger, Patricia, Pfeiffer, Martin, Brecker, Lothar, Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737314/
https://www.ncbi.nlm.nih.gov/pubmed/26565075
http://dx.doi.org/10.1002/anie.201507710