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The role of ADAMTS‐13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies

ESSENTIALS: Molecular diagnostics has improved the differentiation of acute thrombotic microangiopathys (TMAs). Atypical hemolytic uremic syndrome may have features mimicking thrombotic thrombocytopenic purpura. We identified novel complement mutations and a high incidence of CD46, with favorable lo...

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Detalles Bibliográficos
Autores principales: Phillips, E. H., Westwood, J. P., Brocklebank, V., Wong, E. K. S., Tellez, J. O., Marchbank, K. J., McGuckin, S., Gale, D. P., Connolly, J., Goodship, T. H. J., Kavanagh, D., Scully, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737436/
https://www.ncbi.nlm.nih.gov/pubmed/26559391
http://dx.doi.org/10.1111/jth.13189