Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain

Trisomy of human chromosome 21 in Down syndrome (DS) leads to several phenotypes, such as mild-to-severe intellectual disability, hypotonia, and craniofacial dysmorphisms. These are fundamental hallmarks of the disorder that affect the quality of life of most individuals with DS. Proper brain develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Han-Chung, Tan, Kai-Leng, Cheah, Pike-See, Ling, King-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737457/
https://www.ncbi.nlm.nih.gov/pubmed/26881131
http://dx.doi.org/10.1155/2016/7434191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737457/
https://www.ncbi.nlm.nih.gov/pubmed/26881131
http://dx.doi.org/10.1155/2016/7434191

Ejemplares similares