Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)(FBXW11-NSs) E3 Ligase

Activated protein kinase R (PKR) plays a vital role in antiviral defense primarily by inhibiting protein synthesis and augmenting interferon responses. Many viral proteins have adopted unique strategies to counteract the deleterious effects of PKR. The NSs (Non-structural s) protein which is encoded...

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Detalles Bibliográficos
Autores principales: Mudhasani, Rajini, Tran, Julie P., Retterer, Cary, Kota, Krishna P., Whitehouse, Chris A., Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737497/
https://www.ncbi.nlm.nih.gov/pubmed/26837067
http://dx.doi.org/10.1371/journal.ppat.1005437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737497/
https://www.ncbi.nlm.nih.gov/pubmed/26837067
http://dx.doi.org/10.1371/journal.ppat.1005437

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