Cargando…

Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

Genome-wide association studies have successfully identified thousands of loci for a range of human complex traits and diseases. The proportion of phenotypic variance explained by significant associations is, however, limited. Given the same dense SNP panels, mixed model analyses capture a greater p...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Charley, Amador, Carmen, Huffman, Jennifer, Trochet, Holly, Campbell, Archie, Porteous, David, Hastie, Nicholas D., Hayward, Caroline, Vitart, Veronique, Navarro, Pau, Haley, Chris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737500/
https://www.ncbi.nlm.nih.gov/pubmed/26836320
http://dx.doi.org/10.1371/journal.pgen.1005804