Cargando…

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation

Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabolism and signaling. Here, we perform an activity-ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Viader, Andreu, Ogasawara, Daisuke, Joslyn, Christopher M, Sanchez-Alavez, Manuel, Mori, Simone, Nguyen, William, Conti, Bruno, Cravatt, Benjamin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737654/
https://www.ncbi.nlm.nih.gov/pubmed/26779719
http://dx.doi.org/10.7554/eLife.12345