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Central nervous system haemorrhage causing early death in acute promyelocytic leukaemia

Acute promyelocytic leukaemia (APL) is a rare type of paediatric leukaemia characterised by a specific genetic mutation and life-threatening coagulopathy. The discovery of all-trans retinoic acid (ATRA), which acts directly on promyelocytic locus-retinoic acid receptor α (PML-RARα) gene product, bro...

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Detalles Bibliográficos
Autores principales: Borowska, Anna, Stelmaszczyk-Emmel, Anna, Pawelec, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737747/
https://www.ncbi.nlm.nih.gov/pubmed/26862315
http://dx.doi.org/10.5114/ceji.2015.56975