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Up-regulation of liver Pcsk9 gene expression as a possible cause of hypercholesterolemia in experimental chronic renal failure

Dyslipidemia commonly present in patients with chronic kidney disease (CKD) has been recently linked to increased proprotein convertase subtilisin/kexin type 9 (PCSK9) serum concentration. We tested a hypothesis that increased liver PCSK9 biosynthesis could be partially responsible for the elevated...

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Detalles Bibliográficos
Autores principales: Sucajtys-Szulc, Elzbieta, Szolkiewicz, Marek, Swierczynski, Julian, Rutkowski, Boleslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737787/
https://www.ncbi.nlm.nih.gov/pubmed/26481479
http://dx.doi.org/10.1007/s11010-015-2590-0