F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling

During immune surveillance and inflammation, leukocytes exit the vasculature through transient openings in the endothelium without causing plasma leakage. However, the exact mechanisms behind this intriguing phenomenon are still unknown. Here we report that maintenance of endothelial barrier integri...

Descripción completa

Detalles Bibliográficos
Autores principales: Heemskerk, Niels, Schimmel, Lilian, Oort, Chantal, van Rijssel, Jos, Yin, Taofei, Ma, Bin, van Unen, Jakobus, Pitter, Bettina, Huveneers, Stephan, Goedhart, Joachim, Wu, Yi, Montanez, Eloi, Woodfin, Abigail, van Buul, Jaap D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737874/
https://www.ncbi.nlm.nih.gov/pubmed/26814335
http://dx.doi.org/10.1038/ncomms10493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737874/
https://www.ncbi.nlm.nih.gov/pubmed/26814335
http://dx.doi.org/10.1038/ncomms10493

Ejemplares similares