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A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics

Methicillin-resistant Staphylococcus aureus (MRSA) sepsis is a life-threatening medical condition that involves systemic inflammation throughout the body. Glucocorticoids are widely used in combination with antibiotics in the treatment of MRSA sepsis to fight the overwhelming inflammation. Here, we...

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Detalles Bibliográficos
Autores principales: Yang, Yun, Li, Haibo, Sun, Hongwu, Gong, Li, Guo, Ling, Shi, Yun, Cai, Changzhi, Gu, Hao, Song, Zhen, Yang, Liuyang, Tong, Yanan, Wei, Chao, Zou, Quanming, Zeng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738243/
https://www.ncbi.nlm.nih.gov/pubmed/26839286
http://dx.doi.org/10.1038/srep20307