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Presence of retinal pericyte-reactive autoantibodies in diabetic retinopathy patients

The loss of retinal pericytes (RPCs) is a hallmark of early stage diabetic retinopathy (DR), but the mechanism underlying RPC death is unclear. Although it was postulated in previous studies using bovine RPCs that autoantibodies against RPCs might develop and induce RPC death, it is unknown whether...

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Detalles Bibliográficos
Autores principales: Zhang, Lingjun, Li, Yan, Payne, John, Srivastava, Sunil, Fan, Xingjun, Fung, John, Li, Xiaorong, Kern, Timothy S., Lin, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738258/
https://www.ncbi.nlm.nih.gov/pubmed/26839120
http://dx.doi.org/10.1038/srep20341