BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit

The over-expressed colonic brain-derived neurotrophic factor (BDNF) has been reported to be associated with abdominal pain in patients with irritable bowel syndrome (IBS). However, the neuropathological mechanism is unclear. We here investigated the involvement of enteroglial cells (EGCs) and enteri...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Du, Chao, Chen, Fei-Xue, Li, Chang-Qing, Yu, Yan-Bo, Han, Ting, Akhtar, Suhail, Zuo, Xiu-Li, Tan, Xiao-Di, Li, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738267/
https://www.ncbi.nlm.nih.gov/pubmed/26837784
http://dx.doi.org/10.1038/srep20320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738267/
https://www.ncbi.nlm.nih.gov/pubmed/26837784
http://dx.doi.org/10.1038/srep20320

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