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BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit
The over-expressed colonic brain-derived neurotrophic factor (BDNF) has been reported to be associated with abdominal pain in patients with irritable bowel syndrome (IBS). However, the neuropathological mechanism is unclear. We here investigated the involvement of enteroglial cells (EGCs) and enteri...
Autores principales: | Wang, Peng, Du, Chao, Chen, Fei-Xue, Li, Chang-Qing, Yu, Yan-Bo, Han, Ting, Akhtar, Suhail, Zuo, Xiu-Li, Tan, Xiao-Di, Li, Yan-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738267/ https://www.ncbi.nlm.nih.gov/pubmed/26837784 http://dx.doi.org/10.1038/srep20320 |
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