Mathematical modelling of phenotypic plasticity and conversion to a stem-cell state under hypoxia

Hypoxia, or oxygen deficiency, is known to be associated with breast tumour progression, resistance to conventional therapies and poor clinical prognosis. The epithelial-mesenchymal transition (EMT) is a process that confers invasive and migratory capabilities as well as stem cell properties to carc...

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Detalles Bibliográficos
Autores principales: Dhawan, Andrew, Madani Tonekaboni, Seyed Ali, Taube, Joseph H., Hu, Stephen, Sphyris, Nathalie, Mani, Sendurai A., Kohandel, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738268/
https://www.ncbi.nlm.nih.gov/pubmed/26838463
http://dx.doi.org/10.1038/srep18074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738268/
https://www.ncbi.nlm.nih.gov/pubmed/26838463
http://dx.doi.org/10.1038/srep18074

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