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5-HT(2) receptors mediate functional modulation of GABAa receptors and inhibitory synaptic transmissions in human iPS-derived neurons

Neural progenitors differentiated from induced pluripotent stem cells (iPS) hold potentials for treating neurological diseases. Serotonin has potent effects on neuronal functions through multiple receptors, underlying a variety of neural disorders. Glutamate and GABA receptors have been proven funct...

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Detalles Bibliográficos
Autores principales: Wang, Haitao, Hu, Lingli, Liu, Chunhua, Su, Zhenghui, Wang, Lihui, Pan, Guangjin, Guo, Yiping, He, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738270/
https://www.ncbi.nlm.nih.gov/pubmed/26837719
http://dx.doi.org/10.1038/srep20033