A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2

Using a series of immunoprecipitation (IP) – tandem mass spectrometry (LC-MS/MS) experiments and reciprocal BLAST, we conducted a fly-human cross-species comparison of the phosphoinositide-3-kinase (PI3K) interactome in a drosophila S2R+ cell line and several NSCLC and human multiple myeloma cell li...

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Detalles Bibliográficos
Autores principales: Breitkopf, Susanne B., Yang, Xuemei, Begley, Michael J., Kulkarni, Meghana, Chiu, Yu-Hsin, Turke, Alexa B., Lauriol, Jessica, Yuan, Min, Qi, Jie, Engelman, Jeffrey A., Hong, Pengyu, Kontaridis, Maria I., Cantley, Lewis C., Perrimon, Norbert, Asara, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738311/
https://www.ncbi.nlm.nih.gov/pubmed/26839216
http://dx.doi.org/10.1038/srep20471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738311/
https://www.ncbi.nlm.nih.gov/pubmed/26839216
http://dx.doi.org/10.1038/srep20471

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