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Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology

Lysosomal calcium (Ca(2+)) release mediated by NAADP triggers signalling cascades that regulate many cellular processes. The identification of two-pore channel 2 (TPC2) as the NAADP receptor advances our understanding of lysosomal Ca(2+) signalling, yet the lysosome is not amenable to traditional pa...

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Detalles Bibliográficos
Autores principales: Lee, Claire Shuk-Kwan, Tong, Benjamin Chun-Kit, Cheng, Cecily Wing-Hei, Hung, Harry Chun-Hin, Cheung, King-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738322/
https://www.ncbi.nlm.nih.gov/pubmed/26838264
http://dx.doi.org/10.1038/srep20282