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Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology
Lysosomal calcium (Ca(2+)) release mediated by NAADP triggers signalling cascades that regulate many cellular processes. The identification of two-pore channel 2 (TPC2) as the NAADP receptor advances our understanding of lysosomal Ca(2+) signalling, yet the lysosome is not amenable to traditional pa...
Autores principales: | Lee, Claire Shuk-Kwan, Tong, Benjamin Chun-Kit, Cheng, Cecily Wing-Hei, Hung, Harry Chun-Hin, Cheung, King-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738322/ https://www.ncbi.nlm.nih.gov/pubmed/26838264 http://dx.doi.org/10.1038/srep20282 |
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