Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer’s disease mouse models

Alzheimer’s disease (AD) is characterised by amyloid-beta (Aβ) protein deposition in the brain. Posttranslational modifications in Aβ play an important role in Aβ deposition. Tissue transglutaminase (tTG) is an enzyme involved in posttranslational cross-linking of proteins. tTG levels and activity a...

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Detalles Bibliográficos
Autores principales: Wilhelmus, Micha M. M., de Jager, Mieke, Smit, August B., van der Loo, Rolinka J., Drukarch, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738336/
https://www.ncbi.nlm.nih.gov/pubmed/26837469
http://dx.doi.org/10.1038/srep20569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738336/
https://www.ncbi.nlm.nih.gov/pubmed/26837469
http://dx.doi.org/10.1038/srep20569

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