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The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

Rhabdoid tumours (RTs) are highly aggressive tumours of infancy, frequently localized in the central nervous system (CNS) where they are termed atypical teratoid/rhabdoid tumours (AT/RTs) and characterized by bi-allelic inactivation of the SMARCB1 tumour suppressor gene. In this study, by temporal c...

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Detalles Bibliográficos
Autores principales: Han, Zhi-Yan, Richer, Wilfrid, Fréneaux, Paul, Chauvin, Céline, Lucchesi, Carlo, Guillemot, Delphine, Grison, Camille, Lequin, Delphine, Pierron, Gaelle, Masliah-Planchon, Julien, Nicolas, André, Ranchère-Vince, Dominique, Varlet, Pascale, Puget, Stéphanie, Janoueix-Lerosey, Isabelle, Ayrault, Olivier, Surdez, Didier, Delattre, Olivier, Bourdeaut, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738337/
https://www.ncbi.nlm.nih.gov/pubmed/26818002
http://dx.doi.org/10.1038/ncomms10421