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Variation is function: Are single cell differences functionally important?: Testing the hypothesis that single cell variation is required for aggregate function

There is a growing appreciation of the extent of transcriptome variation across individual cells of the same cell type. While expression variation may be a byproduct of, for example, dynamic or homeostatic processes, here we consider whether single‐cell molecular variation per se might be crucial fo...

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Detalles Bibliográficos
Autores principales: Dueck, Hannah, Eberwine, James, Kim, Junhyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738397/
https://www.ncbi.nlm.nih.gov/pubmed/26625861
http://dx.doi.org/10.1002/bies.201500124