Four‐factor prothrombin complex concentrate reverses apixaban‐associated bleeding in a rabbit model of acute hemorrhage

BACKGROUND: Apixaban is a direct factor Xa inhibitor approved for the treatment and prevention of thromboembolic disease. There is a lack of data regarding its reversal in cases of acute bleeding or prior to emergency surgery that needs addressing. OBJECTIVES: This study assessed whether a four‐fact...

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Detalles Bibliográficos
Autores principales: Herzog, E., Kaspereit, F., Krege, W., Mueller‐Cohrs, J., Doerr, B., Niebl, P., Dickneite, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
COAGULATION
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738416/
https://www.ncbi.nlm.nih.gov/pubmed/26447393
http://dx.doi.org/10.1111/jth.13165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738416/
https://www.ncbi.nlm.nih.gov/pubmed/26447393
http://dx.doi.org/10.1111/jth.13165

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