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Nkx3.1 controls the DNA repair response in the mouse prostate

BACKGROUND: The human prostate tumor suppressor NKX3.1 mediates the DNA repair response and interacts with the androgen receptor to assure faithful completion of transcription thereby protecting against TMPRSS2‐ERG gene fusion. To determine directly the effect of Nkx3.1 in vivo we studied the DNA re...

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Detalles Bibliográficos
Autores principales: Zhang, Hailan, Zheng, Tian, Chua, Chee Wai, Shen, Michael, Gelmann, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738428/
https://www.ncbi.nlm.nih.gov/pubmed/26660523
http://dx.doi.org/10.1002/pros.23131