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Macrophage Exosomes Induce Placental Inflammatory Cytokines: A Novel Mode of Maternal–Placental Messaging

Exosome trafficking from the placenta into the maternal circulation is well documented; the possibility that this trafficking is bi‐directional was unknown. We demonstrated clathrin‐mediated endocytosis of macrophage exosomes by the human placenta. We also demonstrated that macrophage exosomes induc...

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Detalles Bibliográficos
Autores principales: Holder, Beth, Jones, Tessa, Sancho Shimizu, Vanessa, Rice, Thomas F., Donaldson, Beverly, Bouqueau, Marielle, Forbes, Karen, Kampmann, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738478/
https://www.ncbi.nlm.nih.gov/pubmed/26602702
http://dx.doi.org/10.1111/tra.12352