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Many Phenotypes Without Many False Discoveries: Error Controlling Strategies for Multitrait Association Studies

The genetic basis of multiple phenotypes such as gene expression, metabolite levels, or imaging features is often investigated by testing a large collection of hypotheses, probing the existence of association between each of the traits and hundreds of thousands of genotyped variants. Appropriate mul...

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Detalles Bibliográficos
Autores principales: Peterson, Christine B., Bogomolov, Marina, Benjamini, Yoav, Sabatti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738479/
https://www.ncbi.nlm.nih.gov/pubmed/26626037
http://dx.doi.org/10.1002/gepi.21942