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Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling

BACKGROUND: Cranial radiotherapy is used to treat tumors of the central nervous system (CNS), as well as non-neoplastic conditions such as arterio-venous malformations; however, its use is limited by the tolerance of adjacent normal CNS tissue, which can lead to devastating long-term sequelae for pa...

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Detalles Bibliográficos
Autores principales: Moravan, Michael J., Olschowka, John A., Williams, Jacqueline P., O’Banion, M. Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738790/
https://www.ncbi.nlm.nih.gov/pubmed/26842770
http://dx.doi.org/10.1186/s12974-016-0496-8