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Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling
BACKGROUND: Cranial radiotherapy is used to treat tumors of the central nervous system (CNS), as well as non-neoplastic conditions such as arterio-venous malformations; however, its use is limited by the tolerance of adjacent normal CNS tissue, which can lead to devastating long-term sequelae for pa...
Autores principales: | Moravan, Michael J., Olschowka, John A., Williams, Jacqueline P., O’Banion, M. Kerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738790/ https://www.ncbi.nlm.nih.gov/pubmed/26842770 http://dx.doi.org/10.1186/s12974-016-0496-8 |
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