Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease

Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids. Progressive neurological deterioration and insurgen...

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Detalles Bibliográficos
Autores principales: D'Arcangelo, G., Grossi, D., Racaniello, M., Cardinale, A., Zaratti, A., Rufini, S., Cutarelli, A., Tancredi, V., Merlo, D., Frank, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738957/
https://www.ncbi.nlm.nih.gov/pubmed/26885401
http://dx.doi.org/10.1155/2016/3830424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738957/
https://www.ncbi.nlm.nih.gov/pubmed/26885401
http://dx.doi.org/10.1155/2016/3830424

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