Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1

In vitro and in vivo imaging of protein tyrosine kinase activity requires minimally invasive, molecularly precise optical probes to provide spatiotemporal mechanistic information of dimerization and complex formation with downstream effectors. We present here a construct with genetically encoded, si...

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Detalles Bibliográficos
Autores principales: Perdios, Louis, Bunney, Tom D., Warren, Sean C., Dunsby, Christopher, French, Paul M.W., Tate, Edward W., Katan, Matilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739061/
https://www.ncbi.nlm.nih.gov/pubmed/26482290
http://dx.doi.org/10.1016/j.jbior.2015.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739061/
https://www.ncbi.nlm.nih.gov/pubmed/26482290
http://dx.doi.org/10.1016/j.jbior.2015.09.002

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