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Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1
In vitro and in vivo imaging of protein tyrosine kinase activity requires minimally invasive, molecularly precise optical probes to provide spatiotemporal mechanistic information of dimerization and complex formation with downstream effectors. We present here a construct with genetically encoded, si...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739061/ https://www.ncbi.nlm.nih.gov/pubmed/26482290 http://dx.doi.org/10.1016/j.jbior.2015.09.002 |