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Validation of a Reversed-Phase High Performance Liquid Chromatography Method for the Simultaneous Analysis of Cysteine and Reduced Glutathione in Mouse Organs

A depletion of reduced glutathione (GSH) has been observed in pathological conditions and in aging. Measuring GSH in tissues using mouse models is an excellent way to assess GSH depletion and the potential therapeutic efficacy of drugs used to maintain and/or restore cellular redox potential. A high...

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Detalles Bibliográficos
Autores principales: Brundu, Serena, Nencioni, Lucia, Celestino, Ignacio, Coluccio, Paolo, Palamara, Anna Teresa, Magnani, Mauro, Fraternale, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739232/
https://www.ncbi.nlm.nih.gov/pubmed/26885246
http://dx.doi.org/10.1155/2016/1746985