Chromosomal disruption and rearrangements during murine sarcoma development converge to stable karyotypic formation kept by telomerase overexpression

BACKGROUND: Tumor initiation presents a complex and unstable genomic landscape; one of the earliest hallmark events of cancer, and its progression is probably based on selection mechanisms under specific environments that lead to functional tumor cell speciation. We hypothesized that viable tumor ph...

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Detalles Bibliográficos
Autores principales: de Oliveira-Júnior, Robson José, Ueira-Vieira, Carlos, Sena, Angela Aparecida Servino, Reis, Carolina Fernandes, Mineo, José Roberto, Goulart, Luiz Ricardo, Morelli, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739385/
https://www.ncbi.nlm.nih.gov/pubmed/26841871
http://dx.doi.org/10.1186/s12929-016-0230-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739385/
https://www.ncbi.nlm.nih.gov/pubmed/26841871
http://dx.doi.org/10.1186/s12929-016-0230-y

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