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Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

BACKGROUND: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections. Nuclear factor-κB is a key component of the TLR-pathway, controlled by inhibitors, encoded by the genes NF...

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Detalles Bibliográficos
Autores principales: Lundbo, Lene F., Harboe, Zitta Barrella, Clausen, Louise N., Hollegaard, Mads V., Sørensen, Henrik T., Hougaard, David M., Konradsen, Helle B., Nørgaard, Mette, Benfield, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739413/
https://www.ncbi.nlm.nih.gov/pubmed/26870821
http://dx.doi.org/10.1016/j.ebiom.2015.11.048