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Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity

Protein-based vaccines offer a safer alternative to live-attenuated or inactivated vaccines but have limited immunogenicity. The identification of adjuvants that augment immunogenicity, specifically in a manner that is durable and antigen-specific, is therefore critical for advanced development. In...

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Detalles Bibliográficos
Autores principales: Martins, Karen A.O., Cooper, Christopher L., Stronsky, Sabrina M., Norris, Sarah L.W., Kwilas, Steven A., Steffens, Jesse T., Benko, Jacqueline G., van Tongeren, Sean A., Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739439/
https://www.ncbi.nlm.nih.gov/pubmed/26870818
http://dx.doi.org/10.1016/j.ebiom.2015.11.041