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Increased IL-21 Expression Induces Granzyme B in Peripheral CD5(+) B Cells as a Potential Counter-Regulatory Effect in Primary Sjögren's Syndrome

Recently, we reported elevated proportions of circulating follicular T helper cells and higher levels of interleukin- (IL-) 21 in primary Sjögren's syndrome (pSS). Interaction of invariant natural killer T (iNKT) cells with B cells and granzyme B (GrB) production may be also important in pSS. T...

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Detalles Bibliográficos
Autores principales: Papp, Gábor, Gyimesi, Edit, Szabó, Krisztina, Zöld, Éva, Zeher, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739475/
https://www.ncbi.nlm.nih.gov/pubmed/26884645
http://dx.doi.org/10.1155/2016/4328372