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Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect

We investigated a polyethylene glycol non-precipitable low-density lipoprotein (LDL) subfraction targeted by IgG and the influence of statin therapy on plasma levels of these small LDL-IgG-immune complexes (LDL-IgG-IC). LDL-subfractions were isolated from 6 atherosclerotic subjects and 3 healthy ind...

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Detalles Bibliográficos
Autores principales: Hörl, Gerd, Froehlich, Harald, Ferstl, Ulrika, Ledinski, Gerhard, Binder, Josepha, Cvirn, Gerhard, Stojakovic, Tatjana, Trauner, Michael, Koidl, Christoph, Tafeit, Erwin, Amrein, Karin, Scharnagl, Hubert, Jürgens, Günther, Hallström, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739583/
https://www.ncbi.nlm.nih.gov/pubmed/26840480
http://dx.doi.org/10.1371/journal.pone.0148210