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Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2

AIMS: Urocortin-1 (Ucn-1) is an endogenous peptide that protects heart from ischemia and reperfusion (I/R) injuries. Ucn-1 is known to prevent cardiac cell death, but its role in the transcription of specific genes related to survival signaling pathway has not been fully defined. The aim of this stu...

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Detalles Bibliográficos
Autores principales: Calderón-Sánchez, Eva, Díaz, Ignacio, Ordóñez, Antonio, Smani, Tarik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739601/
https://www.ncbi.nlm.nih.gov/pubmed/26840743
http://dx.doi.org/10.1371/journal.pone.0147375