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Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

Integrin adhesion complexes (IACs) form mechanochemical connections between the extracellular matrix and actin cytoskeleton and mediate phenotypic responses via posttranslational modifications. Here, we investigate the modularity and robustness of the IAC network to pharmacological perturbation of t...

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Detalles Bibliográficos
Autores principales: Horton, Edward R., Humphries, Jonathan D., Stutchbury, Ben, Jacquemet, Guillaume, Ballestrem, Christoph, Barry, Simon T., Humphries, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739608/
https://www.ncbi.nlm.nih.gov/pubmed/26833789
http://dx.doi.org/10.1083/jcb.201508080